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Microglial contribution to synaptic uptake in the prefrontal cortex in schizophrenia
Neuropathology and Applied Neurobiology ( IF 5 ) Pub Date : 2020-10-05 , DOI: 10.1111/nan.12660
M Tzioras 1, 2 , A J Stevenson 1, 2 , D Boche 3 , T L Spires-Jones 1, 2
Affiliation  

Efficient synaptic communication is crucial to maintain healthy behavioural and cognitive processes. In neurodevelopmental diseases, like schizophrenia, affected individualscan exhibitbehavioural symptoms like psychosis, hallucinations and alterations in decision-making. A reduction in cortical grey matter volume and enlarged ventriclesin the brains of schizophrenia cases has been consistently reported[1,2].

中文翻译:

小胶质细胞对精神分裂症前额叶皮层突触摄取的贡献

有效的突触通信对于维持健康的行为和认知过程至关重要。在神经发育疾病(如精神分裂症)中,受影响的个体会表现出行为症状,如精神病、幻觉和决策改变。一直有报道称精神分裂症患者大脑中皮质灰质体积减少和脑室扩大 [1,2]。
更新日期:2020-10-05
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