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Pyrrolidinyl peptide nucleic acid probes capable of cross-linking with DNA: Effects of terminal and internal modifications on cross-link efficiency.
ChemBioChem ( IF 3.2 ) Pub Date : 2020-09-05 , DOI: 10.1002/cbic.202000589
Penthip Muangkaew 1 , Tirayut Vilaivan 1
Affiliation  

In the middle, on the edge: The DNA crosslinking behaviors of terminally and internally furan‐modified probes are compared. Both the availability of unpaired nucleobases and the stability of the probe‐target complex were important for efficient crosslinking.
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中文翻译:

能够与 DNA 交联的吡咯烷基肽核酸探针:末端和内部修饰对交联效率的影响。

中间,边缘:比较末端和内部呋喃修饰探针的 DNA 交联行为。未配对核碱基的可用性和探针-靶标复合物的稳定性对于有效交联都很重要。
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更新日期:2020-09-05
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