PURPOSE OF REVIEW The aim of the study was to provide an overview of the prevalence, risk factors, burden, and current and emerging pharmacologic treatments for seizure clusters in patients with epilepsy. RECENT FINDINGS Close to half of patients with active epilepsy experience seizure clusters, and the clinical, social, and financial burdens of seizure clusters are high. However, there is no widely accepted definition of seizure clusters; their prevalence is underappreciated, contingencies for addressing them (seizure action plans) are often lacking, and their effects are not well-studied. These issues have resulted in an insufficient number of investigations and approved medications for this condition. Novel formulations are in late-stage development to meet this unmet need.

中文翻译：

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缉获群、救援治疗、缉获行动计划：未满足的需求和新出现的制剂

审查目的 本研究的目的是概述癫痫患者癫痫发作群的患病率、危险因素、负担以及当前和新兴的药物治疗。最近的发现 接近一半的活动性癫痫患者会出现癫痫发作，并且癫痫发作的临床、社会和经济负担都很高。然而，没有广泛接受的癫痫发作定义。它们的普遍性没有得到充分认识，处理它们的应急措施（缉获行动计划）往往缺乏，它们的影响也没有得到充分研究。这些问题导致针对这种情况的调查和批准的药物数量不足。新型配方正处于后期开发阶段，以满足这一未满足的需求。