The bacterial genus Salmonella includes a large group of food-borne pathogens that cause a variety of gastrointestinal or systemic diseases in hosts. Salmonella use several secretion devices to inject various effectors targeting eukaryotic hosts, or bacteria. In the past few years, considerable progress has been made towards understanding the structural features and molecular mechanisms of the secretion systems of Salmonella, particularly regarding their roles in host-pathogen interactions. In this review, we summarize the current advances about the main characteristics of the Salmonella secretion systems. Clarifying the roles of the secretion systems in the process of infecting various hosts will broaden our understanding of the importance of microbial interactions in maintaining human health and will provide information for developing novel therapeutic approaches.

沙门氏菌属细菌包括大量食源性病原体，可导致宿主的各种胃肠道或全身性疾病。沙门氏菌使用几种分泌装置注入针对真核宿主或细菌的各种效应子。在过去的几年中，在了解沙门氏菌分泌系统的结构特征和分子机制方面取得了相当大的进步，特别是关于它们在宿主-病原体相互作用中的作用。在这篇综述中，我们总结了沙门氏菌主要特征的最新进展。分泌系统。阐明分泌系统在感染各种宿主过程中的作用将拓宽我们对微生物相互作用在维持人类健康中的重要性的理解，并将为开发新型治疗方法提供信息。