There is lack of standardization of practices and limited evidence on efficacy and safety of nebulization of antimicrobials. We sought to determine inhalation practices in one tertiary care hospital by performing a cross-sectional survey. Eleven adult ICUs were included in the analysis. Three units followed established protocols. Ventilation circuit filters were exchanged at least daily in all but one units. Dosages of aminoglycosides and CMS depended on indication and unit. Nebulization of antimicrobials was generally regarded as safe and efficacious. Our data indicate that approach to nebulization of antimicrobials may be heterogeneous even in a single center.

中文翻译：

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在德国三级医疗医院中，对机械通气的成年人中的抗菌剂雾化进行异质处理的方法：横断面调查。

缺乏标准化的实践，有关抗菌雾化效果和安全性的证据有限。我们试图通过进行横断面调查来确定一家三级医院的吸入习惯。分析中包括11个成人ICU。三个单位遵循已建立的协议。除一个单元外，至少每天更换通风回路过滤器。氨基糖苷和CMS的剂量取决于适应症和单位。抗菌剂的雾化通常被认为是安全有效的。我们的数据表明，即使在一个中心内，雾化抗生素的方法也可能是异质的。