Abstract Two new mixed-ligand coordination polymers [Zn(bdc)(bib)] n ( 1 , H 2 bdc = 1,3-dicarboxybenzene, bib = 1,3-bis(imidazol-1-yl)benzene) and [Zn(NH 2 -bdc)(bib)] n ( 2 , NH 2 –H 2 bdc = 2-amino-1,4-dicarboxybenzene) are successfully prepared by the reaction of zinc nitrate, N-containing and dicarboxylate ligands under the same hydrothermal conditions. The anti-viability of compounds 1 and 2 is assessed with CCK-8 against SW480 colon cancer cells. To further explore the underlying mechanism of compounds, the cell apoptosis and ROS detection are performed in this experiment.

中文翻译：

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基于羧酸盐和咪唑共配体的两种 Zn(II) 基配位聚合物的结构见解和抗结肠癌活性

摘要 两种新的混合配体配位聚合物 [Zn(bdc)(bib)] n ( 1 , H 2 bdc = 1,3-dicarboxybenzo, bib = 1,3-bis(imidazol-1-yl)benzo) 和 [Zn (NH 2 -bdc)(bib)] n ( 2 , NH 2 –H 2 bdc = 2-amino-1,4-dicarboxybenzo) 由硝酸锌、含氮和二羧酸配体在相同条件下反应成功制备热液条件。用 CCK-8 评估化合物 1 和 2 对 SW480 结肠癌细胞的抗活力。为了进一步探索化合物的潜在机制，本实验进行了细胞凋亡和ROS检测。