In this work, the rod-like 4,4′-bis(imidazol-1-yl)-biphenyl (bibp) ligand is utilized as a building block for the coordination assembly with the Zn(II) ion to produce a new Zn(II)-based coordination polymer [Zn3(bibp)2(HCOO)6](H2O)2 (1) under solvothermal conditions. Furthermore, we use the grinding method to downsize complex 1 to the nanoregion. The anti-gastric cancer activity of the compound is evaluated by the Annexin V-FITC/PI apoptosis assay in flow cytometry, and the following mechanism exploration is performed by the DCFH-DA detection assay for the ROS detection.

中文翻译：

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具有 4,4'-双(1-咪唑基)联苯基配体的 Zn(II) 配位聚合物的合成、晶体结构和抗胃癌活性

在这项工作中，棒状 4,4'-双(咪唑-1-基)-联苯 (bibp) 配体被用作与 Zn(II) 离子配位组装以产生新的 Zn( II) 基配位聚合物 [Zn3(bibp)2(HCOO)6](H2O)2 (1) 在溶剂热条件下。此外，我们使用研磨方法将复合物 1 缩小到纳米区域。通过流式细胞术中的Annexin V-FITC/PI细胞凋亡实验评估该化合物的抗胃癌活性，并通过DCFH-DA检测实验对ROS的检测进行以下机制探索。