Aims To study widefield imaging features, analyse risk factors for progression and compare treatment modalities of peripheral exudative haemorrhagic chorioretinopathy (PEHCR). Methods Clinical and imaging data from each visit were collected, including near-infrared reflectance, fluorescein angiography, indocyanine green angiography, optical coherence tomography using the Spectralis platform (Heidelberg Engineering). Clinical features and treatment performed were recorded. Lesions were classified according to treatments used and according to the prognostic index of macular involvement (MI) and intravitreal bleeding (IVB). Results 50 eyes of 35 patients were retrospectively enrolled. Using widefield imaging, peripheral subretinal fluid (SRF) was detected in 31 (62%) eyes and peripheral neovascular networks were detected in 42 (84%) eyes and graded as focal, diffuse and subtotal in 22 (44%), 17 (34%) and 11 (22%) eyes, respectively. MI secondary to PEHCR during the follow-up was documented in 17 (34%) eyes, while IVB occurred in 7 (14%) eyes. Both MI and IVB correlated with peripheral SRF and lesion grade. Active treatment included anti-vascular endothelial growth factor (anti-VEGF) injections, photodynamic therapy (PDT) and combined anti-VEGF and PDT for 13 (26%), 1 (2%) and 18 (36%) eyes, respectively. In eyes with risk factors, anti-VEGF and combined treatment inversely correlated with MI incidence. Conclusions In our series, peripheral subretinal exudation and the extension of peripheral involvement represented risk factors for MI in eyes with PEHCR. In those high-risk eyes, active treatment is warranted.

中文翻译：

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外周渗出性出血性脉络膜视网膜病变：宽视野成像研究

目的 研究广角成像特征，分析进展的危险因素并比较外周渗出性出血性脉络膜视网膜病变 (PEHCR) 的治疗方式。方法 使用 Spectralis 平台（Heidelberg Engineering）收集每次就诊的临床和影像学数据，包括近红外反射、荧光素血管造影、吲哚菁绿血管造影、光学相干断层扫描。记录临床特征和进行的治疗。根据所使用的治疗方法以及黄斑受累 (MI) 和玻璃体内出血 (IVB) 的预后指数对病变进行分类。结果回顾性入组35例患者50只眼。使用宽场成像，在 31 只（62%）眼中检测到外周视网膜下液（SRF），在 42 只（84%）眼中检测到外周新生血管网络，并在 22 只（44%）、17 只（34%）和 11 只眼中分为局灶性、弥漫性和次全(22%) 眼睛。在随访期间，17 只（34%）眼发生了继发于 PEHCR 的 MI，而 7 只（14%）眼发生了 IVB。MI和IVB都与外周SRF和病变等级相关。积极治疗包括分别对 13 只（26%）、1 只（2%）和 18 只（36%）眼进行抗血管内皮生长因子（抗 VEGF）注射、光动力疗法（PDT）以及联合抗 VEGF 和 PDT。在有危险因素的眼睛中，抗 VEGF 和联合治疗与 MI 发生率呈负相关。结论 在我们的系列中，外周视网膜下渗出和外周受累范围是 PEHCR 眼 MI 的危险因素。在那些高风险的眼睛中，积极的治疗是必要的。