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Targeted Metagenomics Offers Insights into Potential Tickborne Pathogens.
Journal of Clinical Microbiology ( IF 9.4 ) Pub Date : 2020-10-21 , DOI: 10.1128/jcm.01893-20
Matthew Thoendel 1
Affiliation  

Tick-borne disease pathogen identification remains a diagnostic challenge due to the multiple tests necessary for diagnosis. Targeted metagenomic sequencing is an evolving method to detect multiple different pathogens with a single test. In this issue of the Journal of Clinical Microbiology, L. Kingry, S. Sheldon, S. Oatman, B. Pritt, et al. (J Clin Microbiol 58:e00147-20, 2020, https://doi.org/10.1128/JCM.00147-20) explore 16S rRNA gene-targeted metagenomics to identify bacterial pathogens in 881 of more than 13,000 specimens submitted for tick-borne pathogen testing, giving new insights into suspected tick-borne pathogens.

中文翻译:

靶向的元基因组学提供了潜在的T传病原体的见解。

由于诊断需要进行多种检测,因此传播疾病病原体的鉴定仍然是诊断的挑战。靶向宏基因组测序是一种不断发展的方法,可通过一次测试来检测多种不同的病原体。在《临床微生物学杂志》上,L。Kingry,S。Sheldon,S。Oatman,B。Pritt等人。(J Clin Microbiol 58:e00147-20,2020,https://doi.org/10.1128/JCM.00147-20)探索了16S rRNA基因靶向的宏基因组学,以鉴定提交给壁虱的13,000多个标本中的881个细菌病原体。病原体检测,为疑似tick传播的病原体提供新的见解。
更新日期:2020-10-27
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