Adenosine triphosphate (ATP) is a central metabolite that plays an indispensable role in various cellular processes, from energy supply to cell‐to‐cell signaling. Nature has developed sophisticated strategies to use the energy stored in ATP for many metabolic and non‐equilibrium processes, and to sense and bind ATP for biological signaling. The variations in the ATP concentrations from one organelle to another, from extracellular to intracellular environments, and from normal cells to cancer cells are one motivation for designing ATP‐triggered and ATP‐fueled systems and materials, because they show great potential for applications in biological systems by using ATP as a trigger or chemical fuel. Over the last decade, ATP has been emerging as an attractive co‐assembling component for man‐made stimuli‐responsive as well as for fuel‐driven active systems and materials. Herein, current advances and emerging concepts for ATP‐triggered and ATP‐fueled self‐assemblies and materials are discussed, shedding light on applications and highlighting future developments. By bringing together concepts of different domains, that is from supramolecular chemistry to DNA nanoscience, from equilibrium to non‐equilibrium self‐assembly, and from fundamental sciences to applications, the aim is to cross‐fertilize current approaches with the ultimate aim to bring synthetic ATP‐dependent systems closer to living systems.

中文翻译：

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ATP 响应和 ATP 燃料自组装系统和材料。

三磷酸腺苷 (ATP) 是一种中心代谢物，在从能量供应到细胞间信号传导的各种细胞过程中发挥着不可或缺的作用。大自然已经开发出复杂的策略，将 ATP 中储存的能量用于许多代谢和非平衡过程，并感知和结合 ATP 以进行生物信号传导。从一个细胞器到另一个细胞器，从细胞外环境到细胞内环境，从正常细胞到癌细胞，ATP 浓度的变化是设计 ATP 触发和 ATP 燃料系统和材料的一个动机，因为它们在生物应用中显示出巨大的潜力。通过使用 ATP 作为触发器或化学燃料的系统。在过去十年中，ATP 已成为一种有吸引力的联合组装组件，用于人造刺激响应以及燃料驱动的主动系统和材料。本文讨论了 ATP 触发和 ATP 燃料自组装和材料的当前进展和新兴概念，阐明了应用并突出了未来的发展。通过汇集不同领域的概念，即从超分子化学到 DNA 纳米科学，从平衡到非平衡自组装，从基础科学到应用，旨在交叉融合现有方法，最终目标是实现合成ATP 依赖系统更接近生命系统。阐明应用并突出未来发展。通过汇集不同领域的概念，即从超分子化学到 DNA 纳米科学，从平衡到非平衡自组装，从基础科学到应用，旨在交叉融合现有方法，最终目标是实现合成ATP 依赖系统更接近生命系统。阐明应用并突出未来发展。通过汇集不同领域的概念，即从超分子化学到 DNA 纳米科学，从平衡到非平衡自组装，从基础科学到应用，旨在交叉融合现有方法，最终目标是实现合成ATP 依赖系统更接近生命系统。