当前位置: X-MOL 学术J. Photochem. Photobiol. B Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Photodynamic-active smart biocompatible material for an antibacterial surface coating.
Journal of Photochemistry and Photobiology B: Biology ( IF 5.4 ) Pub Date : 2020-09-03 , DOI: 10.1016/j.jphotobiol.2020.112012
Mária Kováčová 1 , Angela Kleinová 1 , Ján Vajďák 2 , Petr Humpolíček 2 , Pavel Kubát 3 , Michal Bodík 4 , Zoran Marković 5 , Zdenko Špitálský 1
Affiliation  

Here we present a new effective antibacterial material suitable for a coating, e.g., surface treatment of textiles, which is also time and financially undemanding. The most important role is played by hydrophobic carbon quantum dots, as a new type of photosensitizer, produced by carbonization of different carbon precursors, which are incorporated by swelling from solution into various polymer matrices in the form of thin films, in particular polyurethanes, which are currently commercially used for industrial surface treatment of textiles. The role of hydrophobic carbon quantum dots is to work as photosensitizers upon irradiation and produce reactive oxygen species, namely singlet oxygen, which is already known as the most effective radical for elimination different kinds of bacteria on the surface or in close proximity to such modified material. Therefore, we have mainly studied the effect of hydrophobic carbon quantum dots on Staphylococcus aureus and the cytotoxicity tests, which are essential for the safe handling of such material. Also, the production of singlet oxygen by several methods (electron paramagnetic spectroscopy, time-resolved near-infrared spectroscopy), surface structures (atomic force microscopy and contact angle measurement), and the effect of radiation on polymer matrices were studied. The prepared material is easily modulated by end-user requirements.



中文翻译:

具有光动力活性的智能生物相容性材料,用于抗菌表面涂层。

在这里,我们提出了一种适用于涂层的新型有效抗菌材料,例如,纺织品的表面处理,这在时间和经济上都不是必需的。最重要的作用是疏水碳量子点,它是一种新型的光敏剂,它是通过碳化不同碳前体而产生的,碳前体通过从溶液中溶胀成薄膜形式的各种聚合物基体,特别是聚氨酯而溶入其中。目前在工业上用于纺织品的工业表面处理。疏水碳量子点的作用是在辐照时充当光敏剂,并产生活性氧,即单线态氧,该单线态氧已被公认为是消除表面上或紧邻此类改性材料的各种细菌的最有效自由基。 。金黄色葡萄球菌和细胞毒性测试,对于安全处理此类材料至关重要。此外,还研究了通过几种方法(电子顺磁光谱法,时间分辨近红外光谱法),表面结构(原子力显微镜和接触角测量)以及辐射对聚合物基质的影响来生产单重态氧。最终用户可以轻松调制所准备的材料。

更新日期:2020-09-10
down
wechat
bug