A portable and compact electron paramagnetic resonance (EPR) imaging magnet was developed for building a 750 MHz EPR imaging system. To realize low-cost fabrication, it was shown that the magnetic homogeneity required for redox EPR imaging using nitroxyl probes can be approximately reproduced by regularly arranging small neodymium magnets that are easy to handle. A five-channel coil driver consisting of operational amplifiers and switching power supplies was developed for field sweep, field modulation, and three field gradients to downsize the imaging system. The EPR imaging of 4-oxo-2,2,6,6-tetramethylpiperidine-d16-1-oxyl (tempone-d16) using a phantom was successfully performed by employing a 3D radial sequence controlled by a digital EPR console.

中文翻译：

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用于生物EPR成像的紧凑排列磁铁的设计与制造

开发了一种便携式紧凑型电子顺磁共振 (EPR) 成像磁体，用于构建 750 MHz EPR 成像系统。为了实现低成本制造，研究表明，通过定期排列易于处理的小型钕磁铁，可以近似再现使用硝酰基探针进行氧化还原 EPR 成像所需的磁性均匀性。开发了由运算放大器和开关电源组成的五通道线圈驱动器，用于场扫描、场调制和三个场梯度，以缩小成像系统的尺寸。4-oxo-2,2,6,6-tetramethylpiperidine-d16-1-oxyl (tempone-d16) 使用幻影的 EPR 成像是通过采用由数字 EPR 控制台控制的 3D 径向序列成功进行的。