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Electrospun antibacterial nanofibers for wound dressings and tissue medicinal fields: A Review
Journal of Innovative Optical Health Sciences ( IF 2.5 ) Pub Date : 2020-07-11 , DOI: 10.1142/s1793545820300128
Zhimei Wei 1 , Liqun Wang 2 , Shouyu Zhang 3 , Tonghai Chen 3 , Jie Yang 1, 4 , Shengru Long 1 , Xiaojun Wang 1
Affiliation  

Bacterial infections are a major cause of chronic infections. Thus, antibacterial material is an urgent need in clinics. Antibacterial nanofibers, with expansive surface area, enable efficient incorporation of antibacterial agents. Meanwhile, structure similar to the extracellular matrix can accelerate cell growth. Electrospinning, the most widely used technique to fabricate nanofiber, is often used in many biomedical applications including drug delivery, regenerative medicine, wound healing and so on. Thus, this review provides an overview of all recently published studies on the development of electrospun antibacterial nanofibers in wound dressings and tissue medicinal fields. This reviewer begins with a brief introduction of electrospinning process and then discusses electrospun fibers by incorporating various types of antimicrobial agents used as in wound dressings and tissue. Finally, we finish with conclusions and further perspectives on electrospun antibacterial nanofibers as 2D biomedicine materials.

中文翻译:

用于伤口敷料和组织医学领域的电​​纺抗菌纳米纤维:综述

细菌感染是慢性感染的主要原因。因此,抗菌材料是临床迫切需要的。具有广阔表面积的抗菌纳米纤维能够有效地掺入抗菌剂。同时,类似于细胞外基质的结构可以加速细胞生长。静电纺丝是制造纳米纤维最广泛使用的技术,通常用于许多生物医学应用,包括药物输送、再生医学、伤口愈合等。因此,本综述概述了所有最近发表的关于电纺抗菌纳米纤维在伤口敷料和组织医学领域的发展的研究。这位审稿人首先简要介绍了静电纺丝工艺,然后讨论了静电纺丝纤维,方法是在伤口敷料和组织中加入各种类型的抗菌剂。最后,我们总结了静电纺抗菌纳米纤维作为二维生物医学材料的结论和进一步的观点。
更新日期:2020-07-11
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