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Electrochemical communication in biofilm of bacterial community.
Journal of Basic Microbiology ( IF 3.1 ) Pub Date : 2020-09-02 , DOI: 10.1002/jobm.202000340
Sounik Manna 1 , Chandan Ghanty 2 , Piyush Baindara 3 , Tarun Kr Barik 4 , Santi M Mandal 1
Affiliation  

Electrochemical communication during biofilm formation has recently been identified. Bacteria within biofilm‐adopt different strategies for electrochemical communication such as direct contact via membrane‐bound molecules, diffusive electron transfer via soluble redox‐active molecules, and ion channel‐mediated long‐range electrochemical signaling. Long‐range electrical signals are important to communicate with distant members within the biofilm, which function through spatially propagating waves of potassium ion (K+) that depolarizes neighboring cells. During propagation, these waves coordinate between the metabolic states of interior and peripheral cells of the biofilm. The understanding of electrochemical communication within the biofilm may provide new strategies to control biofilm‐mediated drug resistance. Here, we summarized the different mechanisms of electrochemical communication among bacterial populations and suggested its possible role in the development of high level of antibiotic resistance. Thus, electrochemical signaling opens a new avenue concerning the electrophysiology of bacterial biofilm and may help to control the biofilm‐mediated infection by developing future antimicrobials.

中文翻译:

细菌群落生物膜中的电化学通讯。

最近已经确定了生物膜形成过程中的电化学交流。生物膜中的细菌采用不同的电化学通讯策略,例如通过膜结合分子直接接触,通过可溶性氧化还原活性分子进行扩散电子转移以及离子通道介导的远程电化学信号传递。远程电信号对于与生物膜中的远距离成员进行通信很重要,后者通过钾离子在空间中的传播而起作用(K +)使相邻细胞消极化。在传播过程中,这些波在生物膜的内部和周围细胞的代谢状态之间进行协调。对生物膜内电化学交流的理解可能提供控制生物膜介导的耐药性的新策略。在这里,我们总结了细菌种群之间电化学交流的不同机制,并提出了其在高水平抗药性发展中的可能作用。因此,电化学信号传导为细菌生物膜的电生理学开辟了一条新途径,并可能通过开发未来的抗菌剂来帮助控制生物膜介导的感染。
更新日期:2020-10-08
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