Development of non-enzymatic glucose sensor is essential to reduce the cost of diabetes regular monitoring. Here, graphitic carbon nitride (g-C₃N₄) is modified with platinum and zinc oxide for non-enzymatic electrochemical glucose sensing in physiological conditions for the first time in the literature. The interactions between Pt, g-C₃N₄ and the ZnO are studied using different physicochemical characterization techniques. The Electrochemical glucose sensing at the ZnO-Pt-gC₃N₄ occurs at low applied potential of +0.20 V (vs. Ag/AgCl) with high sensitivity 3.34 μA/mM/cm² and fast response (5 s) time. This sensor exhibited a wide linear range 0.25–110 mM with lower limit of detection of 0.1 µM. The architectured sensor was evaluated in human blood, serum and urine samples. The sensor is 4 time reusable in whole blood without activity deterioration. This reusable surface helps to reduce the cost of strip.

开发非酶葡萄糖传感器对于降低糖尿病定期监测的成本至关重要。此处，文献中首次在生理条件下用铂和氧化锌修饰了石墨碳氮化物（gC ₃ N ₄），以进行非酶促电化学葡萄糖感测。使用不同的理化表征技术研究了Pt，gC ₃ N ₄和ZnO之间的相互作用。ZnO-Pt-gC ₃ N ₄处的电化学葡萄糖感测发生在+0.20 V（vs. Ag / AgCl）的低施加电势下，具有高灵敏度3.34μA/ mM / cm ²快速响应（5 s）时间。该传感器的线性范围为0.25-110 mM，检测下限为0.1 µM。在人体血液，血清和尿液样本中评估了结构传感器。该传感器可在全血中重复使用4次而不会降低活动性。这种可重复使用的表面有助于降低带钢的成本。