Impaired quality of life (QOL) is common in coronary heart disease and is the major indications for coronary artery bypass graft (CABG) operations. This study aims to compare the QOL of patients with coronary heart disease before and after CABG surgery. A translated Arabic version of the Mac-New health-related QOL questionnaire was used to evaluate QOL improvement in 446 patients who benefited from elective CABG at Nasser Institute for Research and Treatment. There was a statistically significant improvement in physical, emotional, social, and global domains of QOL, as evaluated 3 and 6 months after surgery. Follow-up was 90.4% complete. At 3 months, multiple linear regression has shown that male patients (β = 0.48, p ≤ 0.001) and rural residence (β = 0.39, p ≤ 0.001) were significant independent predictors of improvement in physical QOL domain. While hypercholesterolemia (β = −0.20, −0.49, −0.37, −0.46, p ≤ 0.001), hypertension (β = −0.29, −0.39, p ≤ 0.001, β = −0.35, −β = 0.35, p = 0.001), and smoking (β = −0.79, p ≤ 0.001, β = −0.33, p = 0.04, β = −0.69, p ≤ 0.001, β = −0.47, p = 0.005) were significant predictors of worsening in physical, emotional, social, and global domains, respectively. At 6 months, low preoperative ejection fraction (EF) ≤ 40% was the strongest predictor of improvement (β = 0.54, 0.49, 0.44, and 0.52, p ≤ 0.001) in physical, emotional, social, and global domains of QOL, respectively. But, peripheral vascular disease (PVD) (β = −0.53, p = 0.05, β = −0.81, p = 0.005, β = −0.62, p = 0.03, β = −0.76, p = 0.008) and smoking (β = −0.53, p = 0.001, β = −0.42, p = 0.01, β = −0.42, p = 0.01, β = −0.41, p = 0.02) were significant predictors of worsening in physical, emotional, social, and global domains of QOL, respectively. CABG surgery improved in all domains of QOL. Further studies are required to evaluate changes in QOL at longer period intervals.

中文翻译：

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外科手术心肌血运重建对与健康相关的生活质量的短期结果：阿拉伯MacNew心脏病问卷的验证

生活质量（QOL）受损在冠心病中很常见，并且是冠状动脉搭桥术（CABG）手术的主要指征。本研究旨在比较CABG手术前后冠心病患者的QOL。Mac-New与健康相关的新QOL调查问卷的阿拉伯语翻译版本用于评估纳赛尔研究与治疗研究所选出CABG受益的446例患者的QOL改善。手术后3个月和6个月评估，QOL的身体，情感，社交和全球领域都有统计学上的显着改善。随访完成率为90.4％。在3个月时，多元线性回归显示，男性患者（β= 0.48，p≤0.001）和农村居民（β= 0.39，p≤0.001）是改善身体QOL域的重要独立预测因子。高胆固醇血症（β= -0.20，-0.49，-0.37，-0.46，p≤0.001），高血压（β= -0.29，-0.39，p≤0.001，β= -0.35，-β= 0.35，p = 0.001）和吸烟（β= -0.79，p≤0.001，β= -0.33，p = 0.04，β= -0.69，p≤0.001，β= -0.47，p = 0.005）是身体，情绪，社会领域和全球领域。在6个月时，术前低射血分数（EF）≤40％分别是QOL在身体，情绪，社交和全球范围内改善的最强预测指标（β= 0.54、0.49、0.44和0.52，p≤0.001）。 。但是，周围血管疾病（PVD）（β= -0.53，p = 0.05，β= -0.81，p = 0.005，β= -0.62，p = 0.03，β= -0.76，p = 0.008）和吸烟（β= -0.53，p = 0.001，β= -0.42，p = 0.01，β= -0.42，p = 0.01，β= -0.41，p = 0.02）是身体状况恶化的重要预测指标，QOL的情感，社会和全球领域。在QOL的所有领域，CABG手术均得到改善。需要进一步的研究来评估较长时间间隔内的QOL变化。