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Antiviral Nanostructured Surfaces Reduce the Viability of SARS-CoV-2
ACS Biomaterials Science & Engineering ( IF 5.8 ) Pub Date : 2020-08-31 , DOI: 10.1021/acsbiomaterials.0c01091
Jafar Hasan 1 , Alyssa Pyke 2 , Neelima Nair 2 , Tejasri Yarlagadda 3 , Geoffrey Will 1 , Kirsten Spann 3 , Prasad K D V Yarlagadda 1
Affiliation  

In this letter, we report the ability of the nanostructured aluminum Al 6063 alloy surfaces to inactivate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There was no recoverable viable virus after 6 h of exposure to the nanostructured surface, elucidating a 5-log reduction compared to a flat Al 6063 surface. The nanostructured surfaces were fabricated using wet-etching techniques which generated nanotextured, randomly aligned ridges approximately 23 nm wide on the Al 6063 alloy surfaces. In addition to the excellent mechanical resilience properties previously shown, the etched surfaces have also demonstrated superior corrosion resistance compared to the control surfaces. Such nanostructured surfaces have the potential to be used in healthcare environment such as hospitals and public spaces to reduce the surface transmission of SARS-CoV-2 and combat COVID-19.

中文翻译:

抗病毒纳米结构表面降低 SARS-CoV-2 的活力

在这封信中,我们报告了纳米结构铝 Al 6063 合金表面灭活严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 的能力。暴露于纳米结构表面 6 小时后,没有可恢复的活病毒,说明与平坦的 Al 6063 表面相比,病毒减少了 5 个对数。纳米结构表面是使用湿法蚀刻技术制造的,该技术在 Al 6063 合金表面上产生约 23 nm 宽的纳米纹理、随机排列的脊。除了先前显示的优异的机械弹性性能之外,与对照表面相比,蚀刻表面还表现出优异的耐腐蚀性。这种纳米结构表面有潜力用于医院和公共场所等医疗环境,以减少 SARS-CoV-2 的表面传播并对抗 COVID-19。
更新日期:2020-09-14
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