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Consumption of water contaminated by nitrate and its deleterious effects on the human thyroid gland: a review and update
International Journal of Environmental Health Research ( IF 3.2 ) Pub Date : 2020-08-31 , DOI: 10.1080/09603123.2020.1815664
Edgar García Torres 1 , Rebeca Pérez Morales 2 , Alberto González Zamora 3 , Efraín Ríos Sánchez 1 , Edgar Héctor Olivas Calderón 2 , José de Jesús Alba Romero 2 , Esperanza Yasmín Calleros Rincón 2
Affiliation  

ABSTRACT

Nowadays, the nitrates have been established as carcinogenic components due to the endogenous formation of N-nitroso compounds, however, the consumption of water contaminated with nitrates has only been strongly related to the presence of methemoglobinemia in infants, as an acute effect, leaving out other side effects that demand attention. The thyroid gland takes relevance because it can be altered by many pollutants known as endocrine disruptors, which are agents capable of interfering with the synthesis of hormones, thus far, it is known that nitrates may disrupt the amount of iodine uptake causing most of the time hypothyroidism and affecting the metabolic functions of the organism in all development stages, resulting in an important health burden for the exposed population. Here, this review and update highlighted the impact of consumption of water contaminated with nitrates and effects on the thyroid gland in humans, concluding that nitrates could act as true endocrine disruptor.



中文翻译:

饮用被硝酸盐污染的水及其对人体甲状腺的有害影响:回顾和更新

摘要

目前,由于N的内源性形成,硝酸盐已被确定为致癌成分。-亚硝基化合物,然而,饮用被硝酸盐污染的水仅与婴儿高铁血红蛋白血症的存在密切相关,这是一种急性影响,而忽略了其他需要注意的副作用。甲状腺之所以重要,是因为它可以被许多称为内分泌干扰物的污染物改变,这些污染物是能够干扰激素合成的物质,到目前为止,众所周知,硝酸盐可能会干扰碘的摄取量,从而导致大部分时间甲状腺功能减退并影响生物体在所有发育阶段的代谢功能,对暴露人群造成重要的健康负担。在这里,这篇综述和更新强调了饮用被硝酸盐污染的水的影响以及对人类甲状腺的影响,

更新日期:2020-08-31
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