Endometrial cancer is one of the three most common malignancies in the female genital tract. Previous studies have demonstrated the association between heparanase (HPSE, OMIM 604,724) single‐nucleotide polymorphism (SNP) and cancer risk in several cancers. However, its role in endometrial cancer remains unclear. The present study investigated the effects of HPSE SNPs on the susceptibility and clinicopathological parameters in patients with endometrial cancer.

中文翻译：

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乙酰肝素酶基因多态性与子宫内膜癌易感性的相关性。

子宫内膜癌是女性生殖道中最常见的三种恶性肿瘤之一。先前的研究表明乙酰肝素酶（HPSE，OMIM 604,724）单核苷酸多态性（SNP）与几种癌症的癌症风险之间存在关联。然而，其在子宫内膜癌中的作用仍不清楚。本研究调查了HPSE SNPs对子宫内膜癌患者的敏感性和临床病理参数的影响。