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Advances in immunoassays for organophosphorus and pyrethroid pesticides
Trends in Analytical Chemistry ( IF 13.1 ) Pub Date : 2020-09-01 , DOI: 10.1016/j.trac.2020.116022
Jingjing Yao , Zhongxing Wang , Lingling Guo , Xinxin Xu , Liqiang Liu , Liguang Xu , Shanshan Song , Chuanlai Xu , Hua Kuang

Organophosphorus (OP) and pyrethroid (PYR) pesticides are widely used to control various vectors and pests in agriculture, multiple industries, public health, green area servicing, and water reservoirs, among others. OP and PYR exposure cause respiratory, myocardial, and neuromuscular impairments in humans and acute toxicity in aquatic organisms and honeybees, respectively. Therefore, rapid, easy, sensitive, and quantitative OP and PYR detection methods are required. Immunoassays have been used in the detection of a variety of OP and PYR pesticides. In this review, we report the recent advances in immunoassays for detecting OPs and PYRs with an emphasis on the synthesis of haptens for immunogens and coating antigens, preparation, sensitivity, and specificity of antibodies, and extraction methods of OPs and PYRs. This review will assist in the development of sensitive and accurate analytical assays.



中文翻译:

有机磷和拟除虫菊酯类农药的免疫分析方法的新进展

有机磷(OP)和拟除虫菊酯(PYR)农药广泛用于控制农业,多种工业,公共卫生,绿地服务和水库等中的各种媒介和害虫。暴露于OP和PYR会分别导致人类呼吸道,心肌和神经肌肉损害,以及水生生物和蜜蜂的急性毒性。因此,需要快速,简便,灵敏,定量的OP和PYR检测方法。免疫测定法已用于检测多种OP和PYR农药。在这篇综述中,我们报告了用于检测OP和PYR的免疫测定的最新进展,重点是用于免疫原和包被抗原的半抗原的合成,抗体的制备,敏感性和特异性以及OP和PYR的提取方法。

更新日期:2020-09-16
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