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A Visual Differential Analysis of Structural Features of Internal Cavities in Two Chiral Forms of Diphenylalanine Nanotubes
Biophysics Pub Date : 2020-05-01 , DOI: 10.1134/s0006350920030057
S. V. Filippov , V. S. Bystrov

An original method for visual-differential analysis of conformational features in (bio)macromolecular structures is applied to theoretical study of the differences between the structural organizations of the D and L chiral forms of diphenylalanine nanotubes. Common features in the spatial organization of the inner surfaces of nanotube channels are described: The mirror positions of hydrophilic atoms and equal areas of their projections indicate that the internal surfaces in the channels of diphenylalanine nanotubes of the D and L forms are hydrated similarly. Minor differences have been revealed: a larger channel size in L nanotubes and a greater uniformity in the stacking of diphenylalanine layers in D nanotubes. The results are consistent with the experimental data.

中文翻译:

两种手性形式的二苯丙氨酸纳米管内腔结构特征的视觉差异分析

(生物)大分子结构中构象特征的视觉差异分析的原始方法应用于理论研究二苯丙氨酸纳米管的 D 和 L 手性形式的结构组织之间的差异。描述了纳米管通道内表面空间组织的共同特征: 亲水原子的镜像位置和它们的投影面积相等表明 D 和 L 型二苯丙氨酸纳米管通道中的内表面类似地水合。已揭示出细微差别:L 纳米管中更大的通道尺寸和 D 纳米管中二苯丙氨酸层堆叠的更大均匀性。结果与实验数据一致。
更新日期:2020-05-01
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