Common scab of potato caused by pathogenic Streptomyces species poses an economic burden to commercial potato cultivation. Despite decades of research, no molecular markers linked to this trait are currently available, making the development of scab resistant potato varieties inefficient. We evaluated common scab lesion type and tuber coverage in 198 individuals segregating for common scab resistance in replicated field trials with high natural disease pressure over two growing seasons. To identify genetic features associated with resistance, we genotyped the tetraploid (4x) population and parental lines (Kalkaska and Tundra) using the Illumina Infinium 8303 Potato Array and conducted genome-wide association analysis. Here, we report two significant single nucleotide polymorphism (SNP) markers on chromosome 1 associated with both scab traits in both years as well as a SNP marker on chromosome 2 associated with scab tuber coverage. Gene expression profiling of the parents of this population in response to Thaxtomin A treatment revealed differential expression of genes in tubers putatively involved in cell wall biosynthesis and hormone signaling.

致病性链霉菌引起的马铃薯常见结ab种对商业马铃薯种植造成经济负担。尽管进行了数十年的研究，但目前尚无与该性状相关的分子标记，这使得抗结ab马铃薯品种的开发效率低下。我们在两个自然生长季节的高自然病害压力的重复田间试验中，评估了198个个体的常见sc疮病害类型和块茎覆盖率，针对常见的ab疮病抵抗力进行了隔离。为了鉴定与抗性相关的遗传特征，我们使用Illumina Infinium 8303马铃薯阵列对四倍体（4x）种群和亲本系（Kalkaska和Tundra）进行了基因分型，并进行了全基因组关联分析。这里，我们在两个年份报告了与两个both病相关的1号染色体上的两个重要单核苷酸多态性（SNP）标记，以及与sc块茎覆盖率相关的2号染色体上的两个SNP标记。该人群的亲本对Thaxtomin A处理的基因表达谱分析表明，在块茎中可能参与细胞壁生物合成和激素信号传导的基因差异表达。