当前位置: X-MOL 学术Biosci. Biotechol. Biochem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The structures of cyclic aminals from aldehydes and "roofed" mono-N-sulfonyl cis-diamines.
Bioscience, Biotechnology, and Biochemistry ( IF 1.6 ) Pub Date : 2020-08-30 , DOI: 10.1080/09168451.2020.1811949
Laksana Anugerah Adhi 1 , Satoshi Fukuda 2 , Yukiharu Fukushi 1
Affiliation  

ABSTRACT

Racemic Aldehydes were converted into aminals by using “roofed” mono-N-sulfonyl cis-diamines. Diastereomeric aminals could be separated by silica-gel TLC. The whole configuration of each aminal could be determined by NMR analyses. The chiral reagents were prepared from aminals of racemic reagents and a chiral aldehyde. The reverse may be also true. Epimerization of some aminal remains to be solved.

Abbreviations: RDA-Ms: N-(12-amino-9,10-dihydro-9,10-ethanoanthracen-11-yl)-methylsulfonamide; RDA-Ts: N-(12-amino-9,10-dihydro-9,10-ethanoanthracen-11-yl)-4-methylbenzenesulfonamide; RDA-1Nps: N-(12-amino-9,10-dihydro-9,10-ethanoanthracen-11-yl)-1- naphthylsulfonamide; RDA-2Nps: N-(12-amino-9,10-dihydro-9,10-ethanoanthracen-11-yl)-2-naphthylsulfonamide



中文翻译:

由醛和“屋顶”单-N-磺酰基顺式二胺形成的环状缩醛结构。

摘要

外消旋的醛通过使用“屋顶的”单-N-磺酰基顺式-二胺转化为缩醛。非对映的缩醛可以通过硅胶TLC分离。每个缩醛的整体构型可以通过NMR分析确定。该手性试剂由外消旋试剂的缩醛和手性醛制备。反之亦然。一些氨基酸的差向异构化尚待解决。

缩写:RDA-Ms:N-(12-氨基-9,10-二氢-9,10-乙基蒽蒽-11-基)-甲基磺酰胺;RDA-Ts:N-(12-氨基-9,10-二氢-9,10-乙基蒽基-11-基)-4-甲基苯磺酰胺;RDA-1Nps:N-(12-氨基-9,10-二氢-9,10-乙基蒽基-11-基)-1-萘基磺酰胺;RDA-2Nps:N-(12-氨基-9,10-二氢-9,10-乙基蒽基-11-基)-2-萘基磺酰胺

更新日期:2020-11-05
down
wechat
bug