Immune‐microbiota interaction in Finnish and Russian Karelia young people with high and low allergy prevalence,Clinical & Experimental Allergy

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Immune‐microbiota interaction in Finnish and Russian Karelia young people with high and low allergy prevalence
Clinical & Experimental Allergy ( IF 6.1 ) Pub Date : 2020-09-18 , DOI: 10.1111/cea.13728
Lasse Ruokolainen ₁ , Nanna Fyhrquist _{2,

3} , Tiina Laatikainen _{4,

5} , Petri Auvinen ₆ , Vittorio Fortino ₇ , Giovanni Scala ₈ , Pekka Jousilahti ₄ , Piia Karisola ₃ , Johanna Vendelin ₉ , Antti Karkman ₁ , Olga Markelova ₁₀ , Mika J Mäkelä ₁₁ , Sari Lehtimäki ₁₂ , Joseph Ndika ₃ , Noora Ottman ₂ , Laura Paalanen ₄ , Lars Paulin ₆ , Erkki Vartiainen ₄ , Leena von Hertzen ₁₁ , Dario Greco _{6,

8,

13} , Tari Haahtela ₁₁ , Harri Alenius _{2,

3}

Affiliation

Department of Biosciences, University of Helsinki, Helsinki, Finland.
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Human Microbiome Research (HUMI), University of Helsinki, Helsinki, Finland.
Department of Public Health Solutions, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Institute of Biomedical Technology, University of Tampere, Tampere, Finland.
Unit of Systems Toxicology, Finnish Institute of Occupational Health, Helsinki, Finland.
Petrozavodsk State University, Petrozavodsk, Russia.
Skin and Allergy Hospital, Helsinki University Hospital & University of Helsinki, Helsinki, Finland.
HUSLAB, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

After the Second World War, the population living in the Karelian region was strictly divided by the “iron curtain” between Finland and Russia. This resulted in different lifestyle, standard of living, and exposure to the environment. Allergic manifestations and sensitization to common allergens have been much more common on the Finnish compared to the Russian side.

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