Big Science aims to answer fundamental questions regarding our Universe and represents a great example of how science can lead to innovations that generate a positive impact. Big Science has a great deal of scientific, economic, and social relevance. The objective of this study is to better understand how Big Science impacts innovation through transfer mechanisms and spillovers. To accomplish this objective, this study utilizes a thematic approach to review and organize academic research on Big Science. The main themes emerging from the literature are: technology transfer means and mechanisms, procurement relationships with suppliers, collaboration with public and private sectors, IP strategy and policy, impact of large shared facilities and infrastructures, and entrepreneurship as a result of technology transfer and spillover. Finally, we identify directions for future research.

大科学旨在回答有关我们宇宙的基本问题，并代表科学如何引领创新产生积极影响的一个很好的例子。大型科学具有大量的科学，经济和社会相关性。这项研究的目的是更好地理解大科学如何通过转移机制和溢出效应影响创新。为了实现这一目标，本研究采用主题方法来审查和组织有关大科学的学术研究。从文献中得出的主要主题是：技术转让手段和机制，与供应商的采购关系，与公共和私营部门的合作，知识产权战略和政策，大型共享设施和基础设施的影响以及技术转让和溢出所带来的企业家精神。最后，