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Rare Estradiol Secreting Testicular Mixed Germ Cell Tumor Presenting with Cutaneous Metastasis
Journal of Adolescent and Young Adult Oncology ( IF 2 ) Pub Date : 2021-08-11 , DOI: 10.1089/jayao.2020.0107
Treshita Dey 1 , Nirmalya Banerjee 2 , Rimesh Pal 3
Affiliation  

Germ cell tumors (GCTs) represent the most common form of testicular neoplasms. Metastasis is common in testicular GCTs with lungs, liver, and brain being the common sites of distant tumor spread. Cutaneous metastasis is, however, seldom encountered in testicular GCTs. Herein, we report a rare case of testicular mixed GCT in a 28-year-old male presenting with cutaneous metastasis after orchiectomy. Moreover, the tumor was characterized by estradiol and human chorionic gonadotropin (hCG) cosecretion. Although hCG secretion is not uncommon, autonomous estradiol secretion from GCTs is an extreme oddity.

中文翻译:

罕见的分泌雌二醇的睾丸混合生殖细胞肿瘤出现皮肤转移

生殖细胞肿瘤 (GCT) 是最常见的睾丸肿瘤。转移在睾丸 GCT 中很常见,肺、肝和脑是远处肿瘤扩散的常见部位。然而,在睾丸 GCT 中很少遇到皮肤转移。在此,我们报告了一名 28 岁男性睾丸混合性 GCT 的罕见病例,该男性在睾丸切除术后出现皮肤转移。此外,该肿瘤的特征在于雌二醇和人绒毛膜促性腺激素 (hCG) 共分泌。尽管 hCG 分泌并不少见,但 GCT 的自主雌二醇分泌是一种极端奇怪的现象。
更新日期:2021-08-13
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