当前位置: X-MOL 学术Circ. Res. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Meet the First Author.
Circulation Research ( IF 20.1 ) Pub Date : 2020-08-27 , DOI: 10.1161/res.0000000000000436


Dr Manuel Ehling performed his undergraduate thesis in the lab of Dr Abken at the University Hospital of Cologne (Germany) working on recombinant T-cell receptors. For his PhD thesis, he joined the lab of Dr Adams at the Max-Planck-Institute for Molecular Biomedicine in Muenster, where he focused on developmental angiogenesis. In order to complete his postdoctoral training in a more applied field of research, he joined the lab of Dr Mazzone at VIB in Leuven (Belgium). Here, he analyzed the role of macrophages and endothelial cells during development and in the tumor microenvironment. In his private life, Manuel enjoys running and hiking.


Carlos Flores-Suarez is currently a PhD student in the Wythe Lab at Baylor College of Medicine. Carlos earned his BS in Biology at Universidad Peruana Cayetano Heredia in Peru. His thesis work focuses on the molecular mechanisms controlling arteriovenous identity and how they are dysregulated in arteriovenous malformations. Carlos is interested in biological imaging and quantitative analysis, particularly in animal models of disease. He is drawn to science by his desire to identify novel therapies for genetic diseases. Carlos is excited by his manuscript’s suggestion that inhibiting MEK/ERK signaling may regress sporadic bAVMs caused by somatic activating mutations in KRAS.


Dr Liliana Perdomo is currently a member of Dr Andriantsitohaina’s lab Inserm U1063 at the University Angers, France. Her expertise is in cardiovascular physiology and molecular process in metabolic diseases, like diabetes and obesity. Over the last few years, she worked with extracellular vesicles as a possible marker of metabolic disorders and cardiovascular risk. Dr Perdomo earned her MS-PhD in Biochemistry, Molecular Biology and Biomedicine from the Faculty of Pharmacy of the Universidad Complutense de Madrid, Spain, in the laboratory of Dr M. Benito from the UCM/CAM of Spanish Network of Diabetes (CIBERDEM). Her PhD dissertation was under the mentorship of Dr Almudena Gomez-Hernandez. Dr Perdomo long-term research goal is to find targets to treat metabolic disease and their cardiovascular risk. Outside the lab, she is interested in animal and human integral well-being. In her spare time, she enjoys cooking and gardening.


Wilson Lek Wen Tan is a final year PhD student at the Cardiovascular Research Institute of the National University of Singapore (CVRI, NUS). He completed his BS in Computational Biology at NUS. For his PhD, he has undertaken extensive bioinformatics studies on heart disease noncoding genetics. He has also ventured to the bench to perform experiments involving cardiomyocyte differentiation, cloning and CRISPR-targeting. In the future, Wilson hopes to extend his knowledge in noncoding genetics further to understand the interaction between genetics and epigenetics at the single-cell level. After work, Wilson enjoys a pint of beer, all while still discussing science.


Anene-Nzelu Chukwuemeka George is a Senior Research Fellow at the Cardiovascular Research Institute of the National University of Singapore (CVRI, NUS) and at the Genome Institute of Singapore (GIS). Born in Enugu, Nigeria, he completed his MD at the Latin American School of Medicine, Havana, Cuba, before completing a PhD at NUS. After earning his PhD in 2014, he joined Dr Foo’s lab of “Heart Failure Epigenomics and Molecular Epigenetics” to study the role of chromatin architecture in cardiac development and disease. A major milestone has been establishing the technically demanding methodology of 3C-based assays using human heart tissue in the lab. He is now also focusing on specific noncoding RNA candidates and their role on heart function. Outside the lab, George loves traveling and hiking.


Dr Lídia Cedó earned her BS in Biochemistry and a MS in Nutrition and Metabolism from Universitat Rovira i Virgili of Tarragona. In 2013 she earned her PhD from the same university, focused on the effects of grape seed procyanidins on proliferation and apoptosis of pancreatic cells, under the supervision of Dr Montserrat Pinent. Since 2013, she has worked as a postdoctoral fellow in the Bases Metabòliques del Risc Cardiovascular group, led by Dr Francisco Blanco, from the Institut d’Investigacions Biomèdiques Sant Pau in Barcelona. Her main line of research focuses on the development and metabolic characterization of genetically modified mice as models of dyslipemia (and more specifically in HDL alterations), obesity, diabetes, and arteriosclerosis, and in applied studies of nutritional interventions and pharmacological treatments. Outside the lab, Lídia enjoys sharing her life with her husband and two-year-old daughter. She loves reading and photography and spending time with family and friends.


Dr Yaw Asare is a senior postdoctoral researcher with Dr Martin Dichgans at the Institute for Stroke and Dementia Research, Ludwig-Maximilians-University (LMU) Hospital in Munich (Germany). He earned his BS at KNUST (Ghana) in 2005 and moved to RWTH Aachen University (Germany) for his MS and PhD under the supervision of Dr Jürgen Bernhagen. Yaw has over a decade experience in studying inflammatory mechanisms in atherosclerotic cardiovascular disease with specific interest in NFκB-driven responses. He is currently a co-principal investigator on a DFG-funded CRC1123 project and has received several awards including a “Young Investigator Grant” from LMU. Aside from being a passionate scientist, he is an ordained elder serving the Seventh-day Adventist Church in Munich, a husband of a highly intelligent and supportive wife and father of a lovely son. He can be found on Twitter @Y_Asare_.


Dr Jiangbin Wu earned his BS in Bioengineering from Xi’an Jiaotong University, China and completed his PhD at Tsinghua University, China under the mentorship of Dr Yaou Zhang, where he investigated the regulatory functions of miRNAs in cancer cell cycle regulation. Because of its great impact of cardiovascular disease in human health, he joined Dr Peng Yao’s laboratory in 2016 at Aab Cardiovascular Research Institute of University of Rochester Medical School as a postdoctoral fellow, where he focused on understanding the translational regulation during cardiac fibrosis. Outside of research, he enjoys reading, watching anime, and going outside for hiking.


Fawzia Shahed graduated from St George’s, University London in June 2020 with a BS in Biomedical Science. Her research interests include cardiovascular medicine and pharmacology. She continued this interest through a training year at King’s College London where she worked on cardiovascular research projects.


Dr James Brash earned his PhD in Cardiovascular Science from UCL, where he studied under Dr Christiana Ruhrberg’s supervision and now works as a postdoctoral fellow to investigate the molecular mechanisms of angiogenesis and vascular hyperpermeability. Having used in silico approaches to identify novel mediators of angiogenesis, he teamed up with Rebecca Bolton to generate in vivo data for validating candidate genes. After observing discordant results with constitutive and tamoxifen-inducible gene deletion, they identified endothelial CreER toxicity as a confounding factor. Outside of the lab, James enjoys playing the guitar and practicing Brazilian Jiu-Jitsu.

更新日期:2020-08-28
down
wechat
bug