Subjective and objective cognitive declines are given equal weight as symptoms of pre-mild cognitive impairment in Alzheimer’s disease by recent research criteria. However, the overlap of these constructs is unclear. We used standardized regression-based (SRB) change to define subtle objective cognitive decline across serial neuropsychological assessments. We then examined the associations between objective change and subjective cognitive complaints. Finally, we investigated the impact of different symptom combinations on rates of classification for the early stages of the Alzheimer’s Continuum.

中文翻译：

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A-01主观和主观认知下降为早期阿尔茨海默氏病的补充症状

根据最近的研究标准，主观和客观认知下降的程度与阿尔茨海默氏病轻度认知障碍的症状相同。但是，这些结构的重叠尚不清楚。我们使用标准化的基于回归的（SRB）更改来定义一系列神经心理学评估中的细微客观认知下降。然后，我们研究了客观变化与主观认知障碍之间的关联。最后，我们调查了不同症状组合对阿尔茨海默氏症连续性早期分类率的影响。