This study aimed to develop a procedure for preparing a modified silica-naringin hybrid system. To accomplish, the properties of the obtained material were characterized by FT-IR analysis, UV-Vis spectrophotometry, thermogravimetry, scanning electron microscopy (SEM), and zeta potential. 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was used to characterize and evaluate the antioxidant activity. The naringin release profile at pH = 1.2 and 7.2 were determined. FT-IR studies confirmed the interaction between the naringin and present carrier. The release study indicated that a release an approximately 20% and 50% of the release occurred in the first 30 min in pH = 1.2 and 7.2, respectively. The thermogravimetry and UV-Vis spectrophotometry analysis allowed us to determine the amount of naringin in the studied hybrid material at the level of several percent. The proposed hybrid material shows good stability, as evidenced by the zeta potential of about +30 and −30 mV in an acidic and alkaline environment, respectively. Antioxidant properties are comparable to those of pure naringin. The results suggest that the obtained hybrid material is a promising product with antioxidant properties.

这项研究旨在开发一种程序，用于制备改性的二氧化硅-柚皮苷杂化系统。为此，通过FT-IR分析，UV-Vis分光光度法，热重分析，扫描电子显微镜（SEM）和ζ电势表征了获得的材料的性质。2,2-二苯基-1-吡啶并肼基（DPPH）测定用于表征和评估抗氧化活性。测定在pH ＝ 1.2和7.2下的柚皮苷释放曲线。FT-IR研究证实了柚皮苷和当前载体之间的相互作用。释放研究表明，在pH = 1.2和7.2的前30分钟内，分别发生了约20％和50％的释放。热重分析法和紫外可见分光光度法分析使我们能够确定所研究的混合材料中柚皮苷的含量为百分之几。所提出的杂化材料显示出良好的稳定性，如分别在酸性和碱性环境中的ζ电位约为+30和-30 mV所证明的。抗氧化性能与纯柚皮苷相当。结果表明，获得的杂化材料是具有抗氧化性能的有前途的产品。