Despite several efforts, the development of an effective vaccine for COVID-19 may take a much longer time. Traditional/natural medicine, already experienced by humans, could be an earlier solution. Considering the research team’s experience in using nano-clays as high-affinity material for cancer metastasis, melanoma treatment, and bone regeneration, we propose to use these nano-clays for the prevention/treatment of COVID-19. Owing to high affinity, nano-clays would capture the viruses before the latter get engaged with human hACE2. In this study, molecular-level simulations and modeling of the interaction of coronavirus spike and hACE2 proteins were performed with and without nano-clays. The results showed a very high level of affinity/cohesiveness among SARS-CoV-2 spike and nano-clays as compared to the one between the former and hACE2. We premise that these nano-clays since already being used as drug carriers could also be injected as “clays-alone” medicine. Recommendations have also been provided for future in vitro and in vivo studies.

尽管付出了许多努力，但为COVID-19开发有效的疫苗可能需要更长的时间。人类已经体验过的传统/天然医学可能是更早的解决方案。考虑到研究团队在使用纳米粘土作为高亲和力材料进行癌症转移，黑色素瘤治疗和骨骼再生方面的经验，我们建议将这些纳米粘土用于预防/治疗COVID-19。由于具有高亲和力，纳米粘土会在病毒与人类hACE2接触之前捕获病毒。在这项研究中，在有和没有纳米粘土的情况下，进行了冠状病毒刺突和hACE2蛋白相互作用的分子水平模拟和建模。结果表明，与前者和hACE2之间的亲和力/粘聚力相比，SARS-CoV-2尖峰和纳米粘土之间的亲和力/亲和力非常高。我们假设这些纳米粘土（自从已经被用作药物载体以来）也可以作为“仅粘土”的药物注射。还为将来的体外和体内研究提供了建议。