Rhipicephalus sanguineus sensu lato (s.l.), also known as the brown dog tick, is among the main tick species involved in the transmission of pathogens to humans and other animals and, therefore, the target of numerous control methods. However, due to the disadvantages of synthetic acaricides, the use of alternative products such as plant derivatives has been encouraged. This study aimed to evaluate the acaricidal potential of acetylcarvacrol and to determine its efficacy at sublethal doses for the control of R. sanguineus s.l. female ticks. In addition, as acetylcarvacrol was applied topically, morphological alterations in the integument were assessed. Acetylation of carvacrol was performed by reaction with acetic anhydride in a sodium hydroxide solution, being confirmed by infrared spectroscopy. The lethal concentration for 50 and 90% (LC₅₀ and LC₉₀) of unfed ticks and the efficacy of acetylcarvacrol in engorged females were determined after the Adult Immersion Test (AIT). For the evaluation of effects of acetylcarvacrol in the integument, routine histological techniques were employed after the AIT. The LC₅₀ and LC₉₀ in unfed females were 2.8 and 7.2 μL/mL, respectively. Regarding reproductive performance, after treatment with 8.0 μL/mL acetylcarvacrol 90.9% control was achieved, as ticks showed the lowest egg production index (EPI), hatching rate (HR), and fecundity rate (FR). In the integument, considerable morphological alterations were observed both in cuticle and epithelium. Thus, acetylcarvacrol affected R. sanguineus s.l. external coating and reproduction when applied at sublethal concentrations, probably contributing to a long-term control.

血红扇头蜱意义上拉托（SL），也被称为棕色狗蜱，是参与病原体传播至人类和其它动物的主要蜱物种之间，因此，许多控制方法的对象。但是，由于合成杀螨剂的缺点，鼓励使用替代产品，例如植物衍生物。这项研究旨在评估乙酰香芹酚的杀螨潜力，并确定其在亚致死剂量下控制红血球菌的功效。sl女性壁虱。另外，当局部施用乙酰基香芹酚时，评估了被膜的形态变化。香芹酚的乙酰化反应是通过与乙酸酐在氢氧化钠溶液中反应进行的，通过红外光谱证实。在成年浸没测试（AIT）后，确定了50％和90％的未进食s的致死浓度（LC ₅₀和LC ₉₀）以及乙酰香芹酚在饱腹雌性动物中的功效。为了评价乙酰甲香酚在皮中的作用，在AIT后采用常规的组织学技术。LC ₅₀和LC ₉₀未进食雌性动物中的分别为2.8和7.2μL/ mL。关于生殖性能，用tick虫显示最低的产卵指数（EPI），孵化率（HR）和繁殖力（FR）后，用8.0μL/ mL乙酰香芹酚处理后达到了90.9％的对照。在被膜中，在表皮和上皮中均观察到相当大的形态变化。因此，当以低于致死浓度的浓度施用时，乙酰香芹酚会影响血红红球菌sl的外部涂层和繁殖，可能有助于长期控制。