Peripheral blood mononuclear cells (PBMCs) were isolated from a 32-year-old female and were reprogrammed to human induced pluripotent stem cells (iPSCs) using non-integrative Sendai viral vectors containing reprogramming factors OCT4, SOX2, KLF4 and cMYC. The ZZUSAHi002-A iPSC line expresses pluripotency markers, exhibits a normal female karyotype (46, XX) and has the capacity to differentiate into three germ layers in vivo. This iPSC line may be used for cell transplantations, drug testing and biological tissue engineering.

中文翻译：

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建立源自健康个体外周血单核细胞的诱导性多能干细胞系（ZZUSAHi002-A）。

从一名32岁女性中分离出外周血单核细胞（PBMC），并使用包含重编程因子OCT4，SOX2，KLF4和cMYC的非整合型仙台病毒载体将其重编程为人诱导的多能干细胞（iPSC）。ZZUSAHi002-A iPSC品系表达多能性标记，表现出正常的雌性核型（46，XX），并具有在体内分化为三个胚层的能力。该iPSC品系可用于细胞移植，药物测试和生物组织工程。