One of the features of the Consortium on Individual Development is the existence of a rodent cohort, in parallel with the human cohorts. Here we give an overview of the current status. We first elaborate on the choice of rat and mouse models mimicking early life adverse or beneficial conditions during development. We performed a systematic literature search on early life adversity and adult social behavior to address the status quo. Next, we describe the behavioral tasks we used and designed to examine behavioral control and social competence in rodents. The results so far indicate that manipulation of the environment in the first postnatal week only subtly affects social behavior. Stronger effects were seen in the model that targeted early adolescence; once adult, these rats are characterized by increased attention, a higher degree of impulsiveness and reduced social interest in peers. Many experiments in our rodent models with tightly controlled conditions were inspired by findings in human cohorts, and now allow in-depth mechanistic investigations. Vice versa, some of the findings in rodents are currently followed up by dedicated investigations in the human cohorts. This exemplifies the added value of animal investigations in a consortium encompassing primarily human developmental cohorts.

个人发展联合会的特点之一是，与人类人群同时存在啮齿动物。在这里，我们给出了当前状态的概述。我们首先详细阐述模仿早期生命过程中不利或有益条件的大鼠和小鼠模型的选择。我们针对早期生活的逆境和成人的社会行为进行了系统的文献检索，以解决现状。接下来，我们描述我们用来检查啮齿动物的行为控制和社交能力的行为任务。迄今为止的结果表明，在产后第一周对环境的操纵只会微妙地影响社会行为。在针对早期青春期的模型中，观察到了更强的效果；一旦成年，这些老鼠的特征是注意力增加，较高的冲动性和对同伴的社会兴趣降低。我们在严格控制条件下的啮齿动物模型中的许多实验均受人类队列研究的启发，现在可以进行深入的机理研究。反之亦然，啮齿动物的一些发现目前正在人类队列中进行专门研究。这体现了在主要涵盖人类发育队列的财团中进行动物研究的附加值。