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Microbial lipases and their industrial applications: a comprehensive review.
Microbial Cell Factories ( IF 6.4 ) Pub Date : 2020-08-26 , DOI: 10.1186/s12934-020-01428-8
Prem Chandra 1 , Enespa 2 , Ranjan Singh 3 , Pankaj Kumar Arora 4
Affiliation  

Lipases are very versatile enzymes, and produced the attention of the several industrial processes. Lipase can be achieved from several sources, animal, vegetable, and microbiological. The uses of microbial lipase market is estimated to be USD 425.0 Million in 2018 and it is projected to reach USD 590.2 Million by 2023, growing at a CAGR of 6.8% from 2018. Microbial lipases (EC 3.1.1.3) catalyze the hydrolysis of long chain triglycerides. The microbial origins of lipase enzymes are logically dynamic and proficient also have an extensive range of industrial uses with the manufacturing of altered molecules. The unique lipase (triacylglycerol acyl hydrolase) enzymes catalyzed the hydrolysis, esterification and alcoholysis reactions. Immobilization has made the use of microbial lipases accomplish its best performance and hence suitable for several reactions and need to enhance aroma to the immobilization processes. Immobilized enzymes depend on the immobilization technique and the carrier type. The choice of the carrier concerns usually the biocompatibility, chemical and thermal stability, and insolubility under reaction conditions, capability of easy rejuvenation and reusability, as well as cost proficiency. Bacillus spp., Achromobacter spp., Alcaligenes spp., Arthrobacter spp., Pseudomonos spp., of bacteria and Penicillium spp., Fusarium spp., Aspergillus spp., of fungi are screened large scale for lipase production. Lipases as multipurpose biological catalyst has given a favorable vision in meeting the needs for several industries such as biodiesel, foods and drinks, leather, textile, detergents, pharmaceuticals and medicals. This review represents a discussion on microbial sources of lipases, immobilization methods increased productivity at market profitability and reduce logistical liability on the environment and user.

中文翻译:

微生物脂肪酶及其工业应用:综合综述。

脂肪酶是用途非常广泛的酶,并引起了多种工业过程的关注。脂肪酶可以从多种来源获得,包括动物、植物和微生物。2018年微生物脂肪酶市场的使用量估计为4.25亿美元,预计到2023年将达到5.902亿美元,自2018年起复合年增长率为6.8%。微生物脂肪酶(EC 3.1.1.3)催化长链脂肪酸的水解。链甘油三酯。脂肪酶的微生物起源在逻辑上是动态的和熟练的,并且还具有广泛的工业用途,可制造改变的分子。独特的脂肪酶(三酰甘油酰基水解酶)催化水解、酯化和醇解反应。固定化使微生物脂肪酶的使用达到了最佳性能,因此适用于多种反应,并且需要增强固定化过程的香气。固定化酶取决于固定化技术和载体类型。载体的选择通常涉及生物相容性、化学和热稳定性、反应条件下的不溶性、易于再生和重复使用的能力以及成本效益。大规模筛选细菌的芽孢杆菌属、无色杆菌属、产碱菌属、节杆菌属、假单胞菌属和真菌的青霉属、镰刀菌属、曲霉属用于脂肪酶生产。脂肪酶作为多用途生物催化剂,在满足生物柴油、食品和饮料、皮革、纺织、洗涤剂、制药和医疗等多个行业的需求方面具有良好的前景。本综述讨论了脂肪酶的微生物来源、固定化方法,提高了市场盈利能力并减少了对环境和用户的后勤责任。
更新日期:2020-08-26
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