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Lifetime co-occurring psychiatric disorders in newly diagnosed adults with attention deficit hyperactivity disorder (ADHD) or/and autism spectrum disorder (ASD).
BMC Psychiatry ( IF 4.4 ) Pub Date : 2020-08-26 , DOI: 10.1186/s12888-020-02828-1
Artemios Pehlivanidis 1 , Katerina Papanikolaou 2 , Vasilios Mantas 1 , Eva Kalantzi 1 , Kalliopi Korobili 1 , Lida-Alkisti Xenaki 1 , Georgia Vassiliou 1 , Charalambos Papageorgiou 1
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Co-occurring psychiatric disorders in adults with Attention Deficit Hyperactivity Disorder (ADHD) and/or Autism Spectrum Disorder (ASD) contribute to the burden of the healthcare and possibly to the delay of diagnosis. Aim of the study was to clinically assess the prevalence and compare lifetime co-occurring psychopathology in a sample of newly diagnosed ADHD and/or ASD adults and discuss the diagnostic challenges they pose. The lifetime prevalence rates of ten of the most frequently co-occurring psychiatric diagnoses was registered in 336 adults of normal intelligence who underwent a thorough clinical evaluation for the diagnosis of ADHD and/or ASD for the first time in their lives. Four study groups were formed: the ADHD (n = 151), the ASD (n = 58), the ADHD+ASD (n = 28) and the nonADHD/nonASD (NN) (n = 88) group. At least one co-occurring psychopathology was found in 72.8% of the ADHD group, in 50% of the ASD group, in 72.4% of the ADHD+ASD group and in 76.1% of the NN group (p = 0.004). In all groups the most frequent psychiatric disorder was depressive disorder. The only significant difference regarding the patterns of psychiatric co-occurrence between the ADHD and the nonADHD groups (ASD and NN groups) was found for SUD (p = 0.001). Also, the proportion of subjects with Bipolar Disorder was significantly greater in the NN group as compared to those with ASD (p = 0.025). Our results support the high prevalence of co-occurring psychiatric disorders in adults with ADHD and/or ASD with the ASD group presenting the lowest rate. The most marked difference between the ADHD and the nonADHD groups was found for SUD. Moreover, our findings highlight the need for a thorough clinical assessment of all referred patients both in the presence and absence of ADHD and/or ASD.

中文翻译:

新近诊断为患有注意力缺陷多动障碍(ADHD)或/和自闭症谱系障碍(ASD)的成年人的终生并发精神病。

患有注意力缺陷多动障碍(ADHD)和/或自闭症谱系障碍(ASD)的成年人同时发生的精神病会加重医疗保健的负担,并可能导致诊断延迟。这项研究的目的是对新诊断的ADHD和/或ASD成人的样本进​​行临床评估,并比较一生中共同发生的心理病理,并讨论他们带来的诊断挑战。在336名正常智力的成年人中,有十种最常见的精神病诊断者的终生患病率得到了记录,这些成年人在其生命中首次接受了全面的临床评估以诊断ADHD和/或ASD。形成了四个研究组:ADHD(n = 151),ASD(n = 58),ADHD + ASD(n = 28)和nonADHD / nonASD(NN)(n = 88)组。在ADHD组的72.8%,ASD组的50%,ADHD + ASD组的72.4%和NN组的76.1%中发现了至少一种同时发生的精神病理学(p = 0.004)。在所有组中,最常见的精神病是抑郁症。对于SUD,发现ADHD组和非ADHD组(ASD和NN组)之间的精神共生模式唯一显着差异(p = 0.001)。此外,与ASD相比,NN组中躁郁症患者的比例显着更高(p = 0.025)。我们的结果支持在患有ADHD和/或ASD的成年人中同时发生的精神疾病的高患病率,而ASD组的患病率最低。对于SUD,ADHD组和非ADHD组之间的差异最为明显。此外,
更新日期:2020-08-26
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