Glaucoma is an ocular disease i.e. more common in older adults with elevated intraocular pressure and a serious threat to vision if it is not controlled. Due to the limitations regarding the conventional form of brinzolamide (Azopt®), two optimum formulations of in situ gel nanoemulsion were developed. To ensure the safety and efficacy of developed formulations for ocular drug delivery, the current study was designed.

中文翻译：

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研究布林佐胺原位凝胶纳米乳剂的眼部毒性潜力和治疗效率。

青光眼是一种眼部疾病，即更常见于眼内压升高的老年人，如果不加以控制，则会严重威胁视力。由于传统形式的布林佐胺 (Azopt®) 存在局限性，因此开发了两种最佳原位凝胶纳米乳剂配方。为确保已开发的眼部给药制剂的安全性和有效性，设计了当前的研究。