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Finding the neural correlates of collaboration using a three-person fMRI hyperscanning paradigm.
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-09-15 , DOI: 10.1073/pnas.1917407117
Hua Xie 1 , Iliana I Karipidis 1 , Amber Howell 1 , Meredith Schreier 1 , Kristen E Sheau 1 , Mai K Manchanda 1 , Rafi Ayub 1, 2 , Gary H Glover 3 , Malte Jung 4 , Allan L Reiss 1, 3 , Manish Saggar 5
Affiliation  

Humans have an extraordinary ability to interact and cooperate with others. Despite the social and evolutionary significance of collaboration, research on finding its neural correlates has been limited partly due to restrictions on the simultaneous neuroimaging of more than one participant (also known as hyperscanning). Several studies have used dyadic fMRI hyperscanning to examine the interaction between two participants. However, to our knowledge, no study to date has aimed at revealing the neural correlates of social interactions using a three-person (or triadic) fMRI hyperscanning paradigm. Here, we simultaneously measured the blood-oxygenation level-dependent signal from 12 triads (n = 36 participants), while they engaged in a collaborative drawing task based on the social game of Pictionary. General linear model analysis revealed increased activation in the brain regions previously linked with the theory of mind during the collaborative phase compared to the independent phase of the task. Furthermore, using intersubject correlation analysis, we revealed increased synchronization of the right temporo‐parietal junction (R TPJ) during the collaborative phase. The increased synchrony in the R TPJ was observed to be positively associated with the overall team performance on the task. In sum, our paradigm revealed a vital role of the R TPJ among other theory-of-mind regions during a triadic collaborative drawing task.



中文翻译:

使用三人 fMRI 超扫描范式寻找协作的神经相关性。

人类具有与他人互动和合作的非凡能力。尽管协作具有社会和进化意义,但由于对多个参与者同时进行神经成像(也称为超扫描)的限制,寻找其神经相关性的研究一直受到限制。几项研究使用二元 fMRI 超扫描来检查两个参与者之间的相互作用。然而,据我们所知,迄今为止还没有任何研究旨在使用三人(或三元)fMRI 超扫描范式来揭示社交互动的神经相关性。在这里,我们同时测量了来自 12 个黑社会(n = 36 名参与者)的血氧水平依赖信号,同时他们参与了基于Pictionary社交游戏的协作绘图任务. 一般线性模型分析显示,与任务的独立阶段相比,在协作阶段之前与心智理论相关的大脑区域的激活增加。此外,使用受试者间相关性分析,我们揭示了在协作阶段右侧颞顶骨交界处(R TPJ)的同步性增加。观察到 R TPJ 中增加的同步性与团队在任务中的整体表现呈正相关。总之,我们的范式揭示了 R TPJ 在三元协作绘图任务中在其他心理理论区域中的重要作用。

更新日期:2020-09-16
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