Power‐frequency electromagnetic fields (PF‐EMFs) at 50 Hz are potential health risk factors. This study aimed to explore the effects of long‐term exposure to 50‐Hz PF‐EMFs on general physiological conditions in Sprague–Dawley (SD) rats. During a 24‐week exposure period, the body mass and water and food intake of the animals were recorded regularly. The hematologic parameters were detected every 12 weeks, and blood chemistry analyses were performed every 4 weeks. After sacrifice, morphology was identified by hematoxylin–eosin, Masson, and immunohistochemical staining. Fibrosis‐related gene expression and oxidative stress status were also detected. Compared with the control group, exposure to 30, 100, or 500 μT PF‐EMF did not exert any effect on body mass, food intake, or water intake. Similarly, no significant differences were found in hematologic parameters or blood chemistry analyses among these groups. Furthermore, morphological assays showed that exposure to PF‐EMFs had no influence on the structure of the liver or kidney. Finally, fibrosis‐related gene expression and oxidative stress status were unaltered by PF‐EMF exposure. The present study indicates that 24 weeks of exposure to PF‐EMFs at intensities of 30, 100, or 500 μT might not affect hemograms, blood chemistry, fibrosis, or oxidative stress in the liver or kidney in SD rats. © 2020 Bioelectromagnetics Society

中文翻译：

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长期50-Hz功率电磁场暴露对Sprague-Dawley大鼠肝脏和肾脏的血常规，血液化学，纤维化和氧化应激状态的影响的研究。

50 Hz的工频电磁场（PF-EMF）是潜在的健康风险因素。本研究旨在探讨长期暴露于50 Hz PF-EMF对Sprague-Dawley（SD）大鼠的一般生理状况的影响。在24周的暴露时间内，定期记录动物的体重，水和食物摄入量。每12周检测一次血液学参数，每4周进行一次血液化学分析。处死后，通过苏木精-伊红，Masson和免疫组织化学染色鉴定形态。还检测了与纤维化相关的基因表达和氧化应激状态。与对照组相比，暴露于30、100或500μTPF-EMF对体重，食物摄入或水摄入量没有任何影响。同样，这些组在血液学参数或血液化学分析上没有发现显着差异。此外，形态学分析表明，暴露于PF-EMFs对肝脏或肾脏的结构没有影响。最后，PF-EMF暴露并未改变与纤维化相关的基因表达和氧化应激状态。本研究表明，在30、100或500μT的强度下暴露于PF-EMF 24周可能不会影响SD大鼠肝脏或肾脏的血红蛋白，血液化学，纤维化或氧化应激。©2020生物电磁学会 PF-EMF暴露未改变与纤维化相关的基因表达和氧化应激状态。本研究表明，在30、100或500μT的强度下暴露于PF-EMF 24周可能不会影响SD大鼠肝脏或肾脏的血红蛋白，血液化学，纤维化或氧化应激。©2020生物电磁学会 PF-EMF暴露未改变与纤维化相关的基因表达和氧化应激状态。本研究表明，在30、100或500μT的强度下暴露于PF-EMF 24周可能不会影响SD大鼠肝脏或肾脏的血红蛋白，血液化学，纤维化或氧化应激。©2020生物电磁学会