PVP/PVA based ferrogel was well fabricated using Freezing-Thawing method with Mn_xFe_3-xO₄-PEG magnetic nanoparticles as filler that was previously synthesized by simple coprecipitation method. This sample was confirmed by functional groups data from the Fourier Transform Infrared (FTIR). The manganese doping (x = 0, 0.5, 0.6, 0.7, and 0.8) was added to enhance the chemical and physical characteristics for increasing the application efficiency. Besides, polyethylene glycol (PEG) polymer was added to stabilize the magnetic nanoparticles through the hydrophilic characteristic. The XRD characterization showed that the crystal structure of Mn_xFe_3-xO₄-PEG nanoparticles corresponded to the magnetite phase with the highest peak at 2θ = 35.5° and had average particle sizes about 10.2 nm. This result was similar to the average crystal size characterized by the TEM instrument about 9.9 nm, and the secondary particle size analyzed by the SAXS instrument. By using the Two-Lognormal model, the secondary particle and primary particle sizes of the sample were successfully analyzed and resulted in the particle size of about 10 nm and 3.3 nm, respectively. To analyze the nanostructure of PVP/PVA hydrogels, meanwhile, the Beaucage and Teubner-Strey models were successfully used and resulted in the crystallite size and the average distance between the crystallite of PVP/PVA hydrogels which were approximately 8.8 and 38.6 nm, respectively. The saturation magnetization trend value of Mn_xFe_3-xO₄-PEG decreased by the addition of Mn and the particle size reduction. Furthermore, Mn_xFe_3-xO₄-PEG nanoparticles showed a superparamagnetic characteristic proven by its coercivity field and remnant magnetization approximated to zero. This result showed that the Mn_xFe_3-xO₄-PEG nanoparticles have the potency on some applications such as drug delivery applications and cellular imaging.

使用Mn _x Fe _3-x O ₄ -PEG磁性纳米粒子作为填充剂，采用冻融法很好地制备了PVP / PVA基铁凝胶，该填充剂以前是通过简单的共沉淀法合成的。该样品已通过傅立叶变换红外（FTIR）的官能团数据得到证实。添加锰掺杂（x  = 0、0.5、0.6、0.7和0.8）以增强化学和物理特性，以提高应用效率。此外，添加聚乙二醇（PEG）聚合物以通过亲水特性稳定磁性纳米颗粒。XRD表征表明Mn _x Fe _3-x O ₄的晶体结构-PEG纳米颗粒对应于磁铁矿相，在2θ处具有最高峰 ＝ 35.5°，平均粒径约为10.2nm。该结果类似于通过TEM仪器表征的平均晶体尺寸为约9.9nm，并且通过SAXS仪器分析了二次粒径。通过使用双对数正态模型，成功地分析了样品的二次粒径和一次粒径，得出的粒径分别约为10 nm和3.3 nm。为了分析PVP / PVA水凝胶的纳米结构，同时成功使用了Beaucage和Teubner-Strey模型，得出的晶体尺寸和PVP / PVA水凝胶的微晶平均距离分别约为8.8和38.6 nm。Mn _x Fe _3-x O ₄的饱和磁化趋势值通过添加Mn和减小粒径，减少了-PEG。此外，Mn _x Fe _3-x O ₄ -PEG纳米颗粒表现出超顺磁特性，这由其矫顽力场证明，剩余磁化强度接近零。该结果表明，Mn _x Fe _3-x O ₄ -PEG纳米颗粒在某些应用中具有效力，例如药物递送应用和细胞成像。