ABSTRACT Diazinon is an organophosphate insecticide commonly used worldwide to chemically control different organisms considered as pests. In the past years, diazinon has been described to have immunotoxic effects in several species. Nile tilapia is a teleost fish with an ecological and economic importance, which is also one of the fishes with the highest consumption around the world. The aim of this study was to evaluate the production of neutrophil extracellular traps (NETs) from fish Nile tilapia (Oreochromis niloticus) exposed to diazinon (0.97, 1.95, and 3.91 mg/L) for 6 and 24 h. The results obtained indicate that the exposure to diazinon per se increases NETs production. Therefore, these results could be involved in the understanding of the inflammatory process induced by exposure to pesticides.

中文翻译：

---

二嗪农急性暴露在尼罗罗非鱼（Oreochromis niloticus）中诱导中性粒细胞胞外陷阱

摘要 二嗪农是一种有机磷杀虫剂，在世界范围内广泛用于化学防治被视为害虫的不同生物。在过去的几年里，二嗪农被描述为对几个物种具有免疫毒性作用。尼罗罗非鱼是一种具有生态和经济重要性的硬骨鱼，也是世界上消费量最高的鱼类之一。本研究的目的是评估尼罗罗非鱼（Oreochromis niloticus）暴露于二嗪农（0.97、1.95 和 3.91 毫克/升）6 和 24 小时后产生的中性粒细胞胞外陷阱 (NET)。获得的结果表明，接触二嗪农本身会增加 NETs 的产生。因此，这些结果可能有助于理解农药暴露引起的炎症过程。