Mucosal immunity defines the relationship of surfaces in contact with the environment and integrates diverse tissues such as epidermis, gum, nose, gut, uterus and prostate with the immune system. Although considered part of a system, each mucosa presents specific immune features beyond the barrier and secretory functions. Information regarding the mucosal immunology of the male reproductive tract and the prostate gland in particular is scarce. In this review, we approach the prostate as an epithelial barrier and as part of the mucosal immune system. Finally, we also raise a series of questions that will improve the understanding of this gland, its role in reproduction and its sensitivity/resistance to disease.

粘膜免疫定义了与环境接触的表面的关系，并将表皮、牙龈、鼻子、肠道、子宫和前列腺等多种组织与免疫系统整合在一起。尽管被认为是系统的一部分，但每个粘膜都呈现出超越屏障和分泌功能的特定免疫特征。关于男性生殖道和特别是前列腺的粘膜免疫学的信息很少。在这篇综述中，我们将前列腺视为上皮屏障和粘膜免疫系统的一部分。最后，我们还提出了一系列问题，以提高对这种腺体、其在繁殖中的作用及其对疾病的敏感性/抵抗力的理解。