The biosynthesized Ag NPs was synthesized by using marine mangrove plant extract Avicennia marina. The synthesized Ag NPs was confirmed by various physiochemical characterization including UV-spectrometer and XRD analysis. In addition, the shape and of the synthesized Ag NPs was morphologically identified by SEM initially and TEM finally. After confirmation, the anti-cancer property of synthesized Ag NPs was confirmed at 50 µg/mL concentration against A549 lung cancer cells by MTT assay. Further, the ability to stimulate the ROS generation and mitochondrial membrane at the IC₅₀ concentration of Ag NPs was confirmed by fluorescence microscopy using DCFH-DA and rhodamine 123 dyes respectively. Finally, the result was concluded that the synthesized Ag NPs has improved anti-cancer activity against A549 cells at lowest concentration.

采用海洋红树植物提取物白骨壤 ( Avicennia marina)合成生物合成的纳米银 (Ag NPs) 。合成的银纳米颗粒通过各种物理化学表征（包括紫外光谱仪和 XRD 分析）得到证实。此外，首先通过SEM和TEM对合成的Ag NPs的形状和形态进行了形态学鉴定。经确认后，通过MTT测定证实了合成的Ag NPs在50 µg/mL浓度下对A549肺癌细胞的抗癌特性。此外，分别使用DCFH-DA和罗丹明123染料通过荧光显微镜证实了Ag NP在IC ₅₀浓度下刺激ROS产生和线粒体膜的能力。最后的结论是，合成的Ag NPs在最低浓度下提高了对A549细胞的抗癌活性。