The aim of our study was assessing the potential of FDG-PET-MRI to overcome limitations of separately performed MRI and PET-FDG and improving the performance of high-grade gliomas evaluation. Combined PET-MRI analysis allowed differentiating between recurrence/progression and radionecrosis with improved diagnostic accuracy (95% vs 63% for PET and 82% for MRI). FDG being a reliable, cost-saving tracer in this indication, combined FDG PET-MRI analysis could play a significant role in the follow-up of high-grade brain tumors.

中文翻译：

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FDG-PET/MR 能否帮助克服序贯 MRI 和 PET-FDG 在鉴别诊断高级别胶质瘤复发/进展和放射性坏死方面的局限性？

我们研究的目的是评估 FDG-PET-MRI 克服单独进行 MRI 和 PET-FDG 的局限性的潜力，并提高高级别胶质瘤评估的性能。联合 PET-MRI 分析允许区分复发/进展和放射性坏死，并提高诊断准确性（PET 为 95% 对 63%，MRI 为 82%）。FDG 是该适应症中一种可靠、节省成本的示踪剂，结合 FDG PET-MRI 分析可以在高级别脑肿瘤的随访中发挥重要作用。