Due to its inherent advantages such as easy recovery and reuse of the catalysts/ reagents, and environmentally friendly nature, the heterogeneous system has gain popularity in the realm of organic synthesis. In recent years, several chemically or biologically potent molecules are achieved through heterogeneous synthesis strategies. By recalling some of the classical fundamentals of the heterogeneous system in important organic synthesis, this mini-review outlines the recent developments in the applications heterogeneous catalysts and reagents; particularly in the solid phase synthesis, esterification and transesterification reactions to produce biodiesel, and Henry reaction.

由于其固有的优点，例如催化剂/试剂的易于回收和再利用，以及环境友好的性质，该非均相体系在有机合成领域中得到普及。近年来，通过异质合成策略获得了几种化学或生物学上有效的分子。通过回顾重要有机合成中非均相体系的一些经典原理，本小型综述概述了非均相催化剂和试剂在应用中的最新进展。特别是在固相合成，酯化和酯交换反应以生产生物柴油以及亨利反应中。