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Epidermal growth factor receptor as a molecular determinant of glioblastoma response to dopamine receptor D2 inhibitors
Neuro-Oncology ( IF 15.9 ) Pub Date : 2020-08-24 , DOI: 10.1093/neuonc/noaa188
Yuyu He 1 , Jie Li 1 , Tomoyuki Koga 1 , Jun Ma 1, 2 , Sanjay Dhawan 1 , Yuta Suzuki 1 , Frank Furnari 3 , Varun V Prabhu 4 , Joshua E Allen 4 , Clark C Chen 1
Affiliation  

There are ongoing clinical trials exploring the efficacy of dopamine receptor D2 (DRD2) inhibition against glioblastomas, the most common primary brain tumor. Here we examine potential molecular determinants of this efficacy.

中文翻译:

表皮生长因子受体作为胶质母细胞瘤对多巴胺受体 D2 抑制剂反应的分子决定因素

正在进行临床试验,探索多巴胺受体 D2 (DRD2) 抑制对胶质母细胞瘤的疗效,胶质母细胞瘤是最常见的原发性脑肿瘤。在这里,我们检查了这种功效的潜在分子决定因素。
更新日期:2020-08-24
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