Volatile short-chain fatty acids such as butyric and acetic acid have been supplemented in poultry rations as a feed ingredient and nutritive supplement. A novel Clostridium fermentation solubles broth (MiruTyton), containing short-chain fatty acids, minerals, and amino acids, was supplemented in a standard corn/soybean meal–based ration at a rate of 750, 1,500, 3,000, and 6,000 mg/kg to achieve approximately 277, 554, 1,108, and 2,216 mg/kg of ammonium butyrate in the diet. After 6 wk, supplementation at all levels did not cause significant changes in the blood parameters or any live performance metric of mixed-sex Cobb-500 broilers (N = 1,920). In addition, administering 6,000 mg/kg of MiruTyton caused no significant lesions in any of the tissue examined except for an increase (P < 0.05) in proventricular gastritis as compared with control. The inclusion of 1,500 and 3,000 mg/kg MiruTyton increased (P < 0.01) blood globulin as compared with the control group, which indicates a higher concentration of antibodies in circulation. This experiment demonstrates that mixed-sex Cobb-500 broilers can tolerate supplemental ammonium butyrate up to 2,216 mg/kg in the ration with no negative impact to live performance.

禽饲料中已添加了挥发性的短链脂肪酸，例如丁酸和乙酸，作为饲料成分和营养补充品。含有短链脂肪酸，矿物质和氨基酸的新型梭状芽孢杆菌发酵可溶性肉汤（MiruTyton）以标准的玉米/豆粕定量日粮添加了750、1,500、3,000和6,000 mg / kg的比例在日粮中达到约277、554、1108和2216 mg / kg的丁酸铵。6周后，所有水平的补充均未引起混合性Cobb-500肉鸡的血液参数或任何实时性能指标的显着变化（N = 1,920）。此外，施用6,000 mg / kg的MiruTyton不会引起所检查的任何组织的明显病变，除了增加（P <0.05）与对照相比在胃前胃炎中。 与对照组相比，包含1,500和3,000 mg / kg的MiruTyton增加了（P <0.01）血液球蛋白，表明循环中抗体浓度更高。该实验表明，混合性别的Cobb-500肉鸡在日粮中可耐受补充丁酸铵，最高可达2216 mg / kg，而对生猪的生长性能没有负面影响。