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Documentation of bioactive principles of the flower from Caralluma retrospiciens (Ehrenb) and in vitro antibacterial activity – Part B
Arabian Journal of Chemistry ( IF 6 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.arabjc.2020.07.023
Saad Saeed Alqahtani , Hafiz A. Makeen , Santhosh Joseph Menachery , Sivakumar Sivagurunthan Moni

Abstract The purpose of this study was to explore the biocomponents of flowers from Caralluma retrospiciens (Ehrenb). The study investigated the FT-IR and GC-MS spectral analysis of flower from C. retrospiciens (Ehrenb). A flower concentrate (FC) was prepared and the functional groups were determined by FT-IR spectroscopy study. FT-IR analysis showed the presence of significant compounds at frequency 3287.45, 2850.32, 2595.91, 2524.69, 2041.07 cm-1. The GC-MS study demonstrated the presence of unique pharmaceutically important compounds. The extract was characterized by the presence of unique compounds such as “7,8-Epoxylanostan-11-ol, 3-acetoxy”, “Tetrahydroaraucarolone”, “Pregnan-20-one, 5,6-epoxy-3-hydroxy-, (3a,5a,6a)-”, “Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester”, “Hexadecanoic acid, methyl ester”, “Dasycarpidan-1-methanol, acetate”, etc. The antibacterial effect of the FC showed a wide spectrum of activity against the screened human pathogenic bacteria. The activity was predominantly against Gram-negative bacteria.

中文翻译:

Caralluma retrospiciens (Ehrenb) 花的生物活性原理和体外抗菌活性的文档 - B 部分

摘要 本研究的目的是探索Caralluma retrospiciens (Ehrenb) 花的生物成分。该研究调查了来自 C. retrospiciens (Ehrenb) 的花的 FT-IR 和 GC-MS 光谱分析。制备花浓缩物 (FC) 并通过 FT-IR 光谱研究确定官能团。FT-IR 分析显示在频率 3287.45、2850.32、2595.91、2524.69、2041.07 cm-1 处存在重要化合物。GC-MS 研究证明存在独特的药学上重要的化合物。该提取物的特征在于存在独特的化合物,例如“7,8-Epoxylanostan-11-ol, 3-acetoxy”、“Tetrahydroaraucarolone”、“Pregnan-20-one、5,6-epoxy-3-hydroxy-、 (3a,5a,6a)-", "苯丙酸, 3,5-双(1,1-二甲基乙基)-4-羟基-, 甲酯", "十六烷酸, 甲酯", “Dasycarpidan-1-甲醇醋酸酯”等。FC的抗菌作用对筛选出的人类致病菌表现出广谱活性。该活性主要针对革兰氏阴性菌。
更新日期:2020-10-01
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