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Electrophilic Reactions of 5-Aryltetrazoles: Synthesis of Isomeric 2-(Adamantan-1-Yl)-5-Nitrophenyl-2 H -Tetrazoles and their Derivatives
Chemistry of Heterocyclic Compounds ( IF 1.5 ) Pub Date : 2020-08-21 , DOI: 10.1007/s10593-020-02758-6
Olga V. Mikolaichuk , Daria V. Spasibenko , Rostislav E. Trifonov

The reaction of isomeric 5-nitrophenyl-NH-tetrazoles with adamantan-1-ol in concentrated sulfuric acid gave rise to new isomeric 2-(adamantan-1-yl)-5-nitrophenyl-2H-tetrazoles, nitration and reduction of which produced the corresponding dinitro and amino derivatives. The structures of the obtained compounds were proved by 1H, 13C NMR spectroscopy and high-resolution mass spectrometry. The thermal stability of the dinitro derivative was studied by the method of synchronous thermal analysis.


中文翻译:

5-芳基四唑的亲电反应:异构的2-(Adamantan-1-Yl)-5-硝基苯基-2 H-四唑及其衍生物的合成

同分异构的5-硝基苯的反应Ñ H-四唑与浓硫酸金刚烷-1-醇产生了新的异构体2-(金刚烷-1-基)-5-硝基苯基-2- ħ -tetrazoles,硝化和减少的产生相应的二硝基和氨基衍生物。所得化合物的结构通过1 H,13 C NMR谱和高分辨率质谱法证实。采用同步热分析方法研究了二硝基衍生物的热稳定性。
更新日期:2020-08-21
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