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Low risk of serological cross-reactivity between dengue and COVID-19.
Memórias do Instituto Oswaldo Cruz ( IF 2.8 ) Pub Date : 2020-08-14 , DOI: 10.1590/0074-02760200225
Michele Spinicci 1 , Alessandro Bartoloni 1 , Antonia Mantella 1 , Lorenzo Zammarchi 1 , Gian Maria Rossolini 1 , Alberto Antonelli 1
Affiliation  

In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.

中文翻译:

登革热与COVID-19之间发生血清学交叉反应的风险低。

在不久的将来,2019年冠状病毒病(COVID-19)和登革热流行的重叠是热带地区的具体威胁。COVID-19和登革热的共同流行可能是低收入和中等收入国家卫生系统面临的巨大挑战。在这项工作中,我们调查了COVID-19与登革热患者之间潜在的血清学交叉反应。在32个COVID-19阳性血清中,未观察到登革热(DENV)IgG / IgM阳性结果。另一方面,使用两种快速检测方法中的每一种,在针对COVID-19抗体测试的44个DENV阳性血清中均观察到一个假阳性结果。迫切需要进一步提供有关COVID-19诊断测试准确性的数据。
更新日期:2020-08-20
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