The Belmont Report was written by a US Commission charged by the US Congress to advise on research supported by the US government. Its focus was understandably domestic. In the 40 years since its publication, clinical research has become increasingly international. Many clinical trials have sites in multiple countries, and many of the host countries are relatively impoverished. Such research raises some distinctive ethical issues. This paper outlines some of the key ethical challenges that have been raised by clinical research conducted in low- and middle-income countries (LMICs) and sponsored by high-income country (HIC) institutions. It then considers whether the Belmont Report has the resources to address these problems and argues that it does not. The article closes by noting some parallels between this international research and domestic US research, which suggest that the US might benefit from the discussions abroad.

中文翻译：

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贝尔蒙特报告中的国际临床研究和正义

贝尔蒙特报告由美国国会任命的一个美国委员会撰写，旨在为美国政府支持的研究提供建议。它的重点是国内是可以理解的。自出版以来的 40 年里，临床研究变得越来越国际化。许多临床试验在多个国家设有站点，许多东道国相对贫困。这样的研究提出了一些独特的伦理问题。本文概述了在低收入和中等收入国家 (LMIC) 并由高收入国家 (HIC) 机构赞助的临床研究中提出的一些关键伦理挑战。然后它考虑贝尔蒙特报告是否有资源来解决这些问题，并认为它没有。